Pancreatic cancer carries a very poor prognosis as most patients are diagnosed at an advanced stage. Now a new BJS (British Journal of Surgery) study indicates that breath analyses may help detect pancreatic cancer earlier, when curative treatments may be possible.
For the study, investigators examined volatile organic compounds in breath samples from patients with localized and metastatic pancreatic cancers, compared with patients with benign pancreatic disease and some with a normal pancreas. Tests identified 12 compounds that were indicative of pancreatic cancer. These compounds were from three main chemical groups, namely aldehydes, alkanes and alcohols.
“The final application of breath testing in the patient care pathway will depend on test sensitivity and specificity in large multicentre clinical trials, and its performance in early pancreatic cancer and high-risk groups,” the authors wrote.
Link to Study: https://onlinelibrary.wiley.com/doi/10.1002/bjs.10909
BJS is published on behalf of the BJS Society Ltd by John Wiley & Sons Ltd. The Journal’s influence and standing has grown over the years through the ownership of its registered charity, the BJS Society. The Society’s objectives are to advance and improve education in surgery and to diffuse knowledge on new and improved methods of teaching and practising surgery in all its branches. It does this primarily through the promotion of the Journal but it has also developed strategic European partnerships. The BJS Council of Management is drawn mainly from these partner surgical associations whose relationship has increased the Journal profile and broadened its attraction globally. The Council is proud of the quality of the journal, the content of which is further enhanced by a hands-on approach by its editorial team in improving submitted manuscripts and the journal content.
BJS is the premier peer-reviewed surgical journal in Europe and one of the top surgical periodicals in the world, with an impact factor of 5.899. Its international readership is reflected in the prestigious international Editorial Board, supported by a panel of over 1200 reviewers worldwide.
BJS features the very best in clinical and laboratory-based research on all aspects of general surgery and related topics. BJS has a tradition of publishing high-quality papers in breast, upper GI, lower GI, vascular, endocrine and surgical sciences.
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